In our center, we can diagnose chromosomal diseases. In this department, chromosomes are obtained from peripheric blood, cord blood, amniotic fluid, placental cells, skin fibroblast, gonad tissue, abort material and tumor cells.
Conventional cytogenetics gives information about all anomalies detectable at microscopic levels in whole genome and therefore, it is accepted as the highest standard in prenatal and postnatal diagnosis.
It is the department wheret we use cytogenetics and molecular methods together.
Quantitative and 5-10Mb sized structural chromosome anomalies can be detected with conventional cytogenetic methods. Submicroscopic changes smaller than 5Mb can’t be detected with conventional cytogenetics but last 15 years, performing Molecular Cytogenetics techniques like FISH and Array-CGH made it possible.
This department monitors and studies the changes at DNA and RNA levels.
Following techniques are used in this laboratory;