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Pharmacogenetics (PGx)

Maximum therapeutic benefit, minimum side effects

Pharmacogenetic (PGx) tests identify how genetic factors affect the way an individual metabolizes and responds to medications. Since everyone has a unique genetic makeup, the same drug can lead to different results or adverse side effects in different people.

Using the insights gained from these tests, personalized treatment plans can be developed specifically for an individual’s genetic profile. This approach helps maximize medication effectiveness while preventing potential side effects.

Nesiller Genetics contributes to safer and more effective treatment planning through pharmacogenetic assessment.

What Do Pharmacogenetic (PGx) Tests Tell Us?

PGx tests provide essential information about an individual’s metabolic rate based on genetic profile. These differences in metabolism directly affect how the body responds to treatment, potentially leading to the following outcomes:

Risk of Drug Toxicity

When the body cannot process a drug properly, it accumulates in the bloodstream at dangerous levels. This leads to severe side effects and Adverse Drug Reactions (ADR). PGx tests help select the safest medication to minimize these risks.

Risk of Hypersensitivity

In some cases, even if drug levels in the blood are normal, an individual’s genetic sensitivity can trigger severe allergic or immune responses. PGx tests help lower risk by guiding the physician to adjust or change the treatment when necessary.

Risk of Treatment Failure

If the body processes a drug too quickly or cannot absorb it effectively, the medication fails to reach therapeutic levels in the bloodstream. As a result, the expected recovery does not occur. PGx tests identify the most effective drug to ensure treatment success.

Why Perform PGx Testing?

For chronic conditions like psychiatry and cardiology, PGx tests offer safe and effective personalized treatments for patients not responding to standard medication. By eliminating uncertainties in the treatment process, this method maximizes the patient’s quality of life.

Pharmacogenetics Panel analyzes critical genetic markers such as DPYD and CYP2C9 to determine drug metabolism and toxicity risks. By identifying these genetic variations, the panel enables the creation of alternative treatment options tailored to the patient’s specific needs.

Feature

Details

Method

NGS (Next-Generation Sequencing)

Coverage

30+ Genes

Sample Requirement

EDTA Blood

Turnaround Time (TAT)

4-6 Weeks


*For a detailed sample collection, please contact our team.

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