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PGT-SR (Structural Rearrangements)

 Genetic Compass for Healthy Generations

PGT-SR enables the detection of aneuploid embryos resulting from structural chromosomal rearrangements, such as translocations and insertions. In cases with a family history of chromosomal translocations, recurrent pregnancy loss associated with structural chromosomal abnormalities, or known structural rearrangement carrier status, chromosomal imbalances beyond the scope of PGT-A can be evaluated using PGT-SR. This helps reduce the risk of adverse pregnancy outcomes associated with structural chromosomal abnormalities by enabling the selection of chromosomally balanced embryos for transfer.

Conditions Screened by PGT-SR:

  • Robertsonian translocations
  • Reciprocal translocations
  • Inversions / Insertions

Technical Specifications

Feature

Details

Method

NGS (Next-Generation Sequencing) + Fragment Analysis

Coverage

All chromosomes (24 Chromosomes)

Sample Requirement

Day 5 biopsy (trophectoderm) 

Turnaround Time (TAT)

Approximately 7-14 days

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