Thrombophilia is a condition in which the blood has an increased tendency to clot. Inherited thrombophilia may predispose individuals to thrombotic events and can adversely affect placental blood flow during pregnancy, increasing the risk of pregnancy-related complications.
Thrombophilia Panel helps guide personalized treatment strategies and clinical follow-up for individuals with a family history of thrombosis or early-onset thrombotic disease.
| Feature |
Details |
| Method |
Targeted mutation analysis |
| Coverage |
F5(Leiden),F2(G20210A),MTHFR(C677T),MTHFR(A1298C) |
| Sample Requirement |
Blood (EDTA Tube) |
| Turnaround Time (TAT) |
1 week |
Which Genes Are Analyzed in the Thrombophilia Genetic Test?
The thrombophilia genetic test can assess specific genetic variants associated with an increased tendency for blood clotting. The Factor V Leiden variant in the F5 gene and the G20210A variant in the F2 gene are genetic changes associated with inherited venous thromboembolism risk. The panel may also include analysis of the MTHFR C677T and A1298C variants; however, these variants are not considered indicators of inherited thrombophilia on their own.
Who May Benefit from Thrombophilia Testing?
Thrombophilia testing may be considered following clinical evaluation in individuals with a personal or family history of blood clots. The need for testing is determined based on the individual’s medical history, previous thrombotic events, and whether the test results may contribute to treatment or follow-up decisions.
How Are Thrombophilia Test Results Interpreted?
Thrombophilia genetic test results are interpreted based on the genetic variants analyzed and the individual’s clinical characteristics. The detection of a genetic variant does not necessarily mean that the individual will develop a blood clot. It is important to evaluate the results alongside the clinical history and other risk factors.
* The genes included in the panel may vary according to clinical requirements and upon request.
**For a detailed sample collection, please contact our team.
