
Pediatric Acute Lymphoblastic Leukemia (ALL) – Relapse Panel is a test panel designed to investigate specific genetic and chromosomal alterations in leukemia cells when the disease returns after treatment. ALL relapse refers to the recurrence of the disease after it has been brought under control with treatment. Alterations involving genes such as IKZF1, CRLF2, MYC, and TP53, as well as specific chromosomal abnormalities, may be important for understanding the biological characteristics of the disease and supporting clinical evaluation. The panel analyzes these alterations using the FISH method.
| Genetic Alteration | Method | Sample Type |
| 7p12.2 IKZF1 | FISH | Bone Marrow / Heparinized Blood |
| Xp22.3 CRLF2 | FISH | Bone Marrow / Heparinized Blood |
| FIPIL1-PDGFRA – CHIC2 (4q12) | FISH | Bone Marrow / Heparinized Blood |
| 8q24.12 – q24.13 C MYC | FISH | Bone Marrow / Heparinized Blood |
| 9p21 del P16/CEP9 | FISH | Bone Marrow / Heparinized Blood |
| t(9;22)(q34;q11.2) | FISH | Bone Marrow / Heparinized Blood |
| 11q22.3 del ATM | FISH | Bone Marrow / Heparinized Blood |
| 11q23 | FISH | Bone Marrow / Heparinized Blood |
| t(12;21)(p13;q22) | FISH | Bone Marrow / Heparinized Blood |
| 14q32 del IgH | FISH | Bone Marrow / Heparinized Blood |
| del 17p13.1 (p53) | FISH | Bone Marrow / Heparinized Blood |
| 19p13 E2A | FISH | Bone Marrow / Heparinized Blood |
19 Mayıs Mah. Çoruh Sok. No:32/1 Fulya, 34394 Şişli / Istanbul, Turkey
Monday - Friday 09:00 - 18:00 Saturday 09:00 - 14:00