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Acute Myeloid Leukemia (AML) Panel

Acute Myeloid Leukemia (AML) is a type of cancer characterized by the uncontrolled proliferation of myeloid cells in the bone marrow, which affects normal blood cell production. Genetic and chromosomal alterations involved in AML play an important role in disease classification, risk assessment, and treatment planning. The Acute Myeloid Leukemia (AML) Panel investigates specific chromosomal abnormalities and genetic alterations using FISH and RT-PCR methods.

Genetic Alteration

Method

Sample Type

5q31 deletion

FISH

Bone marrow / Heparinized blood

7q31 deletion

FISH

Bone marrow / Heparinized blood

Trisomy/Monosomy 7

FISH

Bone marrow / Heparinized blood

Trisomy/Monosomy 8

FISH

Bone marrow / Heparinized blood

t(15;17)(q22;q21)

FISH

Bone marrow / Heparinized blood

t(15;17)

RT-PCR

Bone marrow / EDTA blood

t(8;21)(q22;q22)

FISH

Bone marrow / Heparinized blood

t(8;21)

RT-PCR

Bone marrow / EDTA blood

inv(16)(p13q22)

FISH

Bone marrow / Heparinized blood

inv(16)

RT-PCR

Bone marrow / EDTA blood

t(9;22)(q34;q11.2)

FISH

Bone marrow / Heparinized blood

t(9;22)

RT-PCR

Bone marrow / EDTA blood

11q23

FISH

Bone marrow / Heparinized blood

20q12 deletion

FISH

Bone marrow / Heparinized blood

 

 

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