
The First Step in Family Planning

Genetic Causes of Male Infertility
Male infertility may be associated with various factors affecting sperm production, sperm function, or sperm transport. Y chromosome microdeletions, variants in the CFTR gene, and variants in other genes involved in sperm production are among the genetic causes of male infertility. Genetic testing may help investigate the underlying cause, particularly in cases of azoospermia or severely reduced sperm count.
Who May Consider Genetic Testing for Male Infertility?
Genetic testing for male infertility may be considered following clinical evaluation in cases of very low sperm count, azoospermia, or suspected genetically related infertility. Test selection is planned based on the individual’s reproductive history, semen analysis results, and clinical findings.
How Is the Male Infertility Panel Performed?
The Male Infertility Panel is performed using Next-Generation Sequencing (NGS) on an EDTA whole blood sample. The panel analyzes 139 genes associated with male infertility to investigate genetic variants. The results can be evaluated alongside clinical findings and other test results to support the genetic counseling process.
Feature | Details |
Method | NGS (Next-Generation Sequencing) |
Coverage | 139 genes |
Sample Requirement | Blood (EDTA Tube) |
Turnaround Time (TAT) | 3-4 weeks |
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