
Acute Myeloid Leukemia (AML) is a type of cancer characterized by the uncontrolled proliferation of myeloid cells in the bone marrow, which affects normal blood cell production. Genetic and chromosomal alterations involved in AML play an important role in disease classification, risk assessment, and treatment planning. The Acute Myeloid Leukemia (AML) Panel investigates specific chromosomal abnormalities and genetic alterations using FISH and RT-PCR methods.
Genetic Alteration | Method | Sample Type |
|---|---|---|
5q31 deletion | FISH | Bone marrow / Heparinized blood |
7q31 deletion | FISH | Bone marrow / Heparinized blood |
Trisomy/Monosomy 7 | FISH | Bone marrow / Heparinized blood |
Trisomy/Monosomy 8 | FISH | Bone marrow / Heparinized blood |
t(15;17)(q22;q21) | FISH | Bone marrow / Heparinized blood |
t(15;17) | RT-PCR | Bone marrow / EDTA blood |
t(8;21)(q22;q22) | FISH | Bone marrow / Heparinized blood |
t(8;21) | RT-PCR | Bone marrow / EDTA blood |
inv(16)(p13q22) | FISH | Bone marrow / Heparinized blood |
inv(16) | RT-PCR | Bone marrow / EDTA blood |
t(9;22)(q34;q11.2) | FISH | Bone marrow / Heparinized blood |
t(9;22) | RT-PCR | Bone marrow / EDTA blood |
11q23 | FISH | Bone marrow / Heparinized blood |
20q12 deletion | FISH | Bone marrow / Heparinized blood |
19 Mayıs Mah. Çoruh Sok. No:32/1 Fulya, 34394 Şişli / Istanbul, Turkey
Monday - Friday 09:00 - 18:00 Saturday 09:00 - 14:00