
Chronic Lymphocytic Leukemia (CLL) is a type of blood cancer characterized by the uncontrolled accumulation of mature-appearing lymphocytes in the bone marrow and blood. Genetic and chromosomal alterations associated with CLL are important for understanding the biological characteristics of the disease, assessing risk, and guiding treatment planning. The Chronic Lymphocytic Leukemia (CLL) Panel uses the FISH method to investigate specific chromosomal abnormalities.
Genetic Alteration | Method | Sample Type |
|---|---|---|
t(11;14)(q13;q32) | FISH | Bone marrow / Heparinized blood |
11q22.3 deletion (ATM) | FISH | Bone marrow / Heparinized blood |
13q14.3 deletion | FISH | Bone marrow / Heparinized blood |
13q34 deletion | FISH | Bone marrow / Heparinized blood |
17p13.1 (TP53) deletion | FISH | Bone marrow / Heparinized blood |
Trisomy 12 | FISH | Bone marrow / Heparinized blood |
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