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Chronic Lymphocytic Leukemia (CLL) Panel

Chronic Lymphocytic Leukemia (CLL) is a type of blood cancer characterized by the uncontrolled accumulation of mature-appearing lymphocytes in the bone marrow and blood. Genetic and chromosomal alterations associated with CLL are important for understanding the biological characteristics of the disease, assessing risk, and guiding treatment planning. The Chronic Lymphocytic Leukemia (CLL) Panel uses the FISH method to investigate specific chromosomal abnormalities.

Genetic Alteration

Method

Sample Type

t(11;14)(q13;q32)

FISH

Bone marrow / Heparinized blood

11q22.3 deletion (ATM)

FISH

Bone marrow / Heparinized blood

13q14.3 deletion

FISH

Bone marrow / Heparinized blood

13q34 deletion

FISH

Bone marrow / Heparinized blood

17p13.1 (TP53) deletion

FISH

Bone marrow / Heparinized blood

Trisomy 12

FISH

Bone marrow / Heparinized blood

 

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