{"id":16383,"date":"2026-06-18T23:17:29","date_gmt":"2026-06-18T20:17:29","guid":{"rendered":"https:\/\/nesiller.com\/pediatrik-akut-lenfoblastik-losemi-all-relaps-paneli\/"},"modified":"2026-10-26T12:16:14","modified_gmt":"2026-10-26T09:16:14","slug":"pediatric-acute-lymphoblastic-leukemia-all-relapse-panel","status":"publish","type":"page","link":"https:\/\/nesiller.com\/en\/oncology\/focus-hematology-panels\/pediatric-acute-lymphoblastic-leukemia-all-relapse-panel\/","title":{"rendered":"Pediatric Acute Lymphoblastic Leukemia (ALL) Relapse Panel"},"content":{"rendered":"\t\t
\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t
\n\t\t\t\t
\n\t\t\t\t\t
FOCUS Hematology Panels<\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t

Pediatric Acute Lymphoblastic Leukemia (ALL) Relapse Panel<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Pediatric Acute Lymphoblastic Leukemia (ALL) \u2013 Relapse Panel<\/strong> is a test panel designed to investigate specific genetic and chromosomal alterations in leukemia cells when the disease returns after treatment. ALL relapse refers to the recurrence of the disease after it has been brought under control with treatment. Alterations involving genes such as IKZF1, CRLF2, MYC, and TP53, as well as specific chromosomal abnormalities, may be important for understanding the biological characteristics of the disease and supporting clinical evaluation. The panel analyzes these alterations using the FISH method.<\/p>

\u00a0<\/p>
Genetic Alteration<\/strong><\/td>Method<\/strong><\/td>Sample Type<\/strong><\/td><\/tr>
7p12.2\u00a0 IKZF1<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
Xp22.3\u00a0 CRLF2<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
FIPIL1-PDGFRA – CHIC2 (4q12)<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
8q24.12 – q24.13 C MYC<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
9p21 del\u00a0 P16\/CEP9<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
t(9;22)(q34;q11.2)<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
11q22.3 del\u00a0 ATM<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
11q23\u00a0<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
t(12;21)(p13;q22)\u00a0<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
14q32 del IgH<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
del 17p13.1 (p53)\u00a0<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
19p13 E2A<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

FOCUS Pediatric ALL Relapse Panel analyzes IKZF1 (7p12.2), CRLF2 (Xp22.3), CHIC2 (4q12), MYC, P16 (9p21), t(9;22), ATM (11q22.3), 11q23, t(12;21), IgH (14q32), p53 (17p13.1) and E2A (19p13) alterations by FISH in bone marrow or heparinized blood.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":16386,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-16383","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16383","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/comments?post=16383"}],"version-history":[{"count":25,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16383\/revisions"}],"predecessor-version":[{"id":21997,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16383\/revisions\/21997"}],"up":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16386"}],"wp:attachment":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/media?parent=16383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}