{"id":16379,"date":"2026-06-18T23:40:44","date_gmt":"2026-06-18T20:40:44","guid":{"rendered":"https:\/\/nesiller.com\/kronik-myeloid-losemi-cml-paneli\/"},"modified":"2026-10-26T13:46:54","modified_gmt":"2026-10-26T10:46:54","slug":"chronic-myeloid-leukemia-cml-panel","status":"publish","type":"page","link":"https:\/\/nesiller.com\/en\/oncology\/focus-hematology-panels\/chronic-myeloid-leukemia-cml-panel\/","title":{"rendered":"Chronic Myeloid Leukemia (CML) Panel"},"content":{"rendered":"\t\t
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FOCUS Hematology Panels<\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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Chronic Myeloid Leukemia (CML) Panel<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Chronic Myeloid Leukemia (CML)<\/strong> is a type of blood cancer characterized by the uncontrolled proliferation of myeloid cells in the bone marrow. The disease is most commonly associated with the t(9;22) translocation, which leads to the formation of the Philadelphia chromosome and the resulting BCR::ABL1 fusion gene. The Chronic Myeloid Leukemia (CML) Panel investigates this translocation and certain other chromosomal abnormalities using FISH and RT-PCR methods.<\/p>

\u00a0<\/p>
Genetic Alterations<\/strong><\/td>Method<\/strong><\/td>Sample Type<\/strong><\/td><\/tr>
t(9;22)(q34;q11.2)<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
t(9;22)<\/td>RT-PCR<\/td>Bone Marrow \/ EDTA Blood<\/td><\/tr>
inv(16)(p13q22)<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
inv(16)<\/td>RT-PCR<\/td>Bone Marrow \/ EDTA Blood<\/td><\/tr>
5q31 Deletion<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
7q31 Deletion<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr>
Trisomy \/ Monosomy 8<\/td>FISH<\/td>Bone Marrow \/ Heparinized Blood<\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t
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\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

FOCUS Chronic Myeloid Leukemia (CML) Panel analyzes t(9;22) and inv(16) by FISH and RT-PCR, plus 5q31 and 7q31 deletions and trisomy\/monosomy 8 by FISH, in bone marrow or blood samples.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":16386,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-16379","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/comments?post=16379"}],"version-history":[{"count":24,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16379\/revisions"}],"predecessor-version":[{"id":22022,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16379\/revisions\/22022"}],"up":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/16386"}],"wp:attachment":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/media?parent=16379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}