{"id":12629,"date":"2026-02-12T08:01:05","date_gmt":"2026-02-12T05:01:05","guid":{"rendered":"https:\/\/nesiller.com\/fragile-x\/"},"modified":"2026-10-03T18:35:37","modified_gmt":"2026-10-03T15:35:37","slug":"fragile-x","status":"publish","type":"page","link":"https:\/\/nesiller.com\/en\/carrier-screening\/fragile-x\/","title":{"rendered":"Fragile X"},"content":{"rendered":"\t\t
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Carrier Screening and Reproductive Genetics<\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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Fragile X<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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The First Step in Family Planning<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Fragile X syndrome<\/strong> is one of the most common genetic causes of female infertility and is associated with mutations in the FMR1<\/strong> gene located on the X chromosome. From a reproductive perspective, FMR1<\/strong> premutations are particularly important, as they may predispose individuals to premature ovarian insufficiency<\/strong>.<\/p>

Fragile X syndrome is one of the most common inherited causes of intellectual disability and may be associated with learning difficulties, developmental delay, and behavioral differences.<\/p>

Fragile X Carrier Screening<\/strong> is particularly recommended for women with a family history of Fragile X syndrome, unexplained intellectual disability, or premature ovarian insufficiency. Assessing carrier status in individuals planning a pregnancy or during pregnancy helps identify potential genetic risks and supports informed reproductive decision-making.<\/p>
Feature\u00a0<\/b><\/td>Details<\/b><\/td><\/tr>
Method<\/b><\/td>Fragment Analysis<\/span><\/td><\/tr>
Coverage<\/b><\/td>FMR1<\/span><\/i> gene<\/span><\/td><\/tr>
Sample Requirement\u00a0<\/b><\/td>

Blood (EDTA Tube)<\/span><\/p>

Amniotic Fluid\u00a0<\/span><\/p>

CVS<\/span><\/p>

Saliva<\/p><\/td><\/tr>

Turnaround Time (TAT)\u00a0<\/b><\/td>21 days<\/span><\/td><\/tr><\/tbody><\/table>

* Genetic counseling is recommended for individuals identified as carriers. This provides detailed information about the risk of passing the condition on to their children, available prenatal diagnostic options, and other clinical conditions associated with Fragile X syndrome.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Carrier Screening and Reproductive Genetics Fragile X The First Step in Family […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":12705,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-12629","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/comments?post=12629"}],"version-history":[{"count":16,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12629\/revisions"}],"predecessor-version":[{"id":20807,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12629\/revisions\/20807"}],"up":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12705"}],"wp:attachment":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/media?parent=12629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}