{"id":12605,"date":"2026-02-13T18:51:33","date_gmt":"2026-02-13T15:51:33","guid":{"rendered":"https:\/\/nesiller.com\/cytogenetic-analysis\/"},"modified":"2026-10-03T18:35:10","modified_gmt":"2026-10-03T15:35:10","slug":"cytogenetic-analysis","status":"publish","type":"page","link":"https:\/\/nesiller.com\/en\/prenatal-testing\/cytogenetic-analysis\/","title":{"rendered":"Cytogenetic Analysis"},"content":{"rendered":"\t\t
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Prenatal Tests<\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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Chromosomal Alterations<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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From Uncertainty to Clarity in Prenatal Diagnosis<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Chromosomal abnormalities account for 50\u201360% of recurrent pregnancy losses<\/strong>. Numerical abnormalities (such as trisomies 13, 18, and 21) and structural chromosomal abnormalities are analyzed using FISH, chromosome analysis, and molecular karyotyping techniques.<\/p>

Chromosome Analysis (Karyotyping)<\/b><\/p>

Feature<\/b><\/p><\/td>

Details<\/b><\/p><\/td><\/tr>

Method<\/b><\/p><\/td>

Cell Culture<\/span><\/p><\/td><\/tr>

Coverage<\/b><\/p><\/td>

All chromosomes (24 chromosomes)<\/span><\/p><\/td><\/tr>

Sample Requirement<\/b><\/p><\/td>

Amniotic Fluid (Plungerless syringe)<\/span><\/p>

Maternal blood in EDTA<\/span><\/p>

CVS<\/span><\/p>

Heparinized Blood<\/span><\/p>

Abortus Tissue\u00a0<\/span><\/p>

Cord Blood (Cordocentesis)<\/p><\/td><\/tr>

Turnaround Time (TAT)<\/b><\/p><\/td>

3-4 weeks (Amniocentesis)<\/span><\/p>

2-3 weeks (CVS and Abortus)<\/span><\/p>

15 days (Peripheral Blood)<\/span><\/p><\/td><\/tr><\/tbody><\/table>

\u00a0<\/p>

Rapid Aneuploidy FISH<\/strong><\/p>

Rapid Aneuploidy FISH is routinely recommended and performed at our center, providing rapid detection of common chromosomal aneuploidies in amniotic fluid and CVS specimens.<\/p>

Feature<\/b><\/p><\/td>

Details<\/b><\/p><\/td><\/tr>

Method<\/b><\/p><\/td>

\u00a0FISH<\/span><\/p><\/td><\/tr>

Coverage<\/b><\/p><\/td>

Analysis of chromosomes 13, 18, 21, X, and Y<\/span><\/p><\/td><\/tr>

Sample Requirement<\/b><\/p><\/td>

Fetal Blood<\/span><\/p>

CVS<\/span><\/p>

Amniotic Fluid<\/span><\/p><\/td><\/tr>

Turnaround Time (TAT)<\/b><\/p><\/td>

3-5 days<\/span><\/p><\/td><\/tr><\/tbody><\/table>

\u00a0<\/p>

Molecular Karyotyping\u00a0<\/b><\/p>

Molecular karyotyping enables the detection of chromosomal imbalances, including microdeletions and microduplications, that cannot be identified using conventional cytogenetic methods.<\/p>

Feature<\/b><\/p><\/td>

Details<\/b><\/p><\/td><\/tr>

Method<\/b><\/p><\/td>

Chromosomal Microarray Analysis (aCGH \/ SNP-array)<\/span><\/p><\/td><\/tr>

Coverage<\/b><\/p><\/td>

CNV, del\/dup, LOH<\/span><\/p><\/td><\/tr>

Sample Requirement<\/b><\/p><\/td>

Fetal Blood<\/span><\/p>

CVS<\/span><\/p>

Amniotic Fluid<\/span><\/p>

Cord Blood (Cordocentesis)<\/p>

Heparinized Blood<\/span><\/p><\/td><\/tr>

Turnaround Time (TAT)<\/b><\/p><\/td>

2-3 weeks<\/span><\/p><\/td><\/tr><\/tbody><\/table>


<\/span>Maternal blood must be submitted alongside prenatal samples to exclude Maternal Cell Contamination.
*<\/span>For a detailed sample collection, please contact our team.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Prenatal Tests Chromosomal Alterations From Uncertainty to Clarity in Prenatal Diagnosis Chromosomal […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":12699,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-12605","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12605","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/comments?post=12605"}],"version-history":[{"count":22,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12605\/revisions"}],"predecessor-version":[{"id":20831,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12605\/revisions\/20831"}],"up":[{"embeddable":true,"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/pages\/12699"}],"wp:attachment":[{"href":"https:\/\/nesiller.com\/en\/wp-json\/wp\/v2\/media?parent=12605"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}