Consanguineous marriage is an important factor that affects genetic diseases’ epidemiology and consanguineous marriage rate is over 25% in Turkey. Hereditary diseases show up as a result of changes or mutations in heritage materials called genes. In these changed or mutated genes, the ones that cause a disease even when they are single dose are called dominant genes and the diseases are called dominant diseases. The other group is ressesive genes and cause a disease when they are double doses and the diseases are called ressesive diseases. Disordered genes tend to come together more often in consanguineous marriages or closed societies, so in consanguineous marriages, ressesive hereditary diseases appear more frequently.
Consanguineous marriages increase the possibility of harmful dominant and ressesive genes, therefore can cause genetic diseases. Both parents having at least one harmful ressesive genes result the offsprings have the condition. Accordingly, consanguineous marriages in the family that have same gene structure, will increase probability of ressesive genes and will increase the possibility of offsprings with anomalies. We, as Nesiller Genetik, evaluate couples who made or are about to make consanguineous marriages considering their genetic structure and inform them what precautions should be taken.